Diazepan Prodes 10mg Tablets

£20.00£80.00

Category: Anti-anxiety

Active ingredient: Diazepam
This medicine contains lactose
The other ingredients are maize starch, croscarmellose sodium, povidone (E-1201), colloidal silica, magnesium stearate (E 470b), talc and indigotine (E-132).
30 Long-acting tablets

Therapeutic indications

Diazepan Prodes is prescribed for the treatment of anxiety, agitation, and psychic tension. It is also prescribed for patients with alcohol deprivation. Diazepan Prodes, is a benzodiazepine derivative that has tranquilizing, sedative, muscle relaxant, anticonvulsant (for seizures) and antipsychotic activity.

This drug may also be used together with other medicinal products in the treatment of seizure disorders as it has not been shown to be useful as a single treatment. In these cases, the doctor should periodically evaluate the usefulness of the medicine for each patient.

Contraindications

Avoid the use of Diazepan Prodes in the following cases:

  • if you are allergic (hypersensitive) to diazepam or any of the other ingredients of Diazepan Prodes;
  • If you are dependent on other substances, including alcohol;
  • If you have closed-angle glaucoma (increased tension in the eye) and have severe chronic hypercapnia (increased carbon dioxide or CO2 in the blood).

Side effects

Like any other drug, Diazepan Prodes can have some side effects which may occur during the course of taking this medicine, such as:

  • Fatigue;
  • Drowsiness;
  • muscle weakness;
  • anterograde amnesia (lack of memory);
  • confusion;
  • constipation;
  • depression;
  • diplopia (double vision);
  • difficulty articulating words;
  • headache;
  • hypotension (low blood pressure);
  • disorders of libido (sexual appetite),;
  • nausea;
  • dry mouth or secretion of saliva exaggerated;
  • skin rashes;
  • tremor;
  • urinary retention;
  • vertigo;
  • blurred vision.

If any of the mentioned side effects gets serious, please immediately contact your doctor or pharmacist.

SKU: Diazepan Prodes 10 mg Category: Tag:

Description

Pharmacology

Diazepan Prodes belongs to the group of benzodiazepines and has a tranquilizing, sedative, muscle relaxant, anticonvulsant (for seizures) and antipsychotic effect. Usually, this drug is prescribed to people who have anxiety, agitation, and psychic tension due to psychoneurotic states and transient situational disorders. It is also prescribed for patients with alcohol deprivation, as it may help for symptomatic relief from acute agitation, tremor, and hallucinations. Diazepan Prodes is also can be used together with other medicines to relieve musculoskeletal pain due to spasms (contractures) or local pathology (inflammation of muscles or joints, trauma, etc.). Additionally, it can be used to treat spasticity (rigidity) in conditions such as cerebral palsy and paraplegia, as well as involuntary movements and generalized stiffness syndrome. Diazepan Prodes is effective together with other medicinal products in the treatment of seizure disorders as it has not been shown to be useful as a single treatment. In these cases, the doctor should periodically evaluate the usefulness of the medicine for each patient.

Benzodiazepine class of drugs act on the brain and nerves (central nervous system) to produce a calming effect. Benzodiazepine is a strong sedative/hypnotic that has a variety of effects by modulating the GABA subtype of the GABA receptor, the most prolific inhibitory receptor within the brain. Its relaxant effect is also due to the inhibition of spinal reflexes. Benzodiazepines bind non-specifically to the benzodiazepine receptor site and magnifying the efficiency and effects of the neurotransmitter gamma-aminobutyric acid (GABA) by acting on its receptors. Used for things like insomnia, seizures, anxiety, affects muscle relaxation, motor coordination, and memory.

Pharmacokinetics

Diazepan Prodes is completely and rapidly absorbed from the gastrointestinal tract. The peak plasma concentration is achieved in 30-90 minutes after oral ingestion. Intramuscular absorption is erroneous, partly depending on the depth of the injection, the site, and the amount of fat and the possible precipitation of the drug at the injection site. After administration i.m. plasma concentrations are lower than those observed after oral administration. The clinical action appears after 30 minutes (absorption time).

Indications

Diazepan Prodes is not a generic drug. It can’t be used for long-term treatment. Use this drug exactly as prescribed by your doctor. The duration of treatment should be as short as possible. Overall the total duration of treatment should not exceed 8-12 weeks including the gradual withdrawal of treatment. Diazepan Prodes is used in the treatment of anxiety disorders, alcohol withdrawal symptoms, muscle spasms, sometimes can be used with other medications to treat seizures. Each tablet contains Diazepan Prodes 10 mg. Ask your doctor or pharmacist if you have any questions.

Dosage and administration

The dose of Diazepan Prodes 10 mg tablets should be as prescribed by your doctor according to your individual needs.

Adults:

  • Symptoms of anxiety: 2 to 10 mg, 2 to 4 times a day, depending on the severity of the symptoms;
  • Symptomatic relief in acute alcoholic deprivation: 10 mg, 3 or 4 times during the first 24 hours, reducing to 5 mg, 3 or 4 times a day, as needed;
  • Along with other medicines for the relief of spasm or skeletal muscle contracture: 2 to 10 mg, 3 or 4 times a day;
  • Along with other medicines in anticonvulsant therapy (for seizures): 2 to 10 mg, 2 or 4 times a day.

Children:

  • 2 to 2.5 mg, 1 or 2 times a day, gradually increasing according to needs and tolerance; as a general rule 0.1-0.3 mg/kg per day. Because of the variety of response of children to medications that act on the Central Nervous System, treatment should be initiated at the lowest dose and increased as needed. This drug can’t be given to children under 6 months of age.

Elderly patients with kidney or liver disease:

–          2 to 2.5 mg, 1 or 2 times a day, then gradually increase a dose according to need and tolerance.

Special attention will be given in patients with kidney or liver disease when individualizing the dose. If you think the action of Diazepan Prodes 10 mg tablets is too strong or too weak, consult with your doctor or pharmacist. Do not stop treatment before your doctor tells you to do so and under the conditions prescribed by your doctor.

After six weeks of treatment, no further improvement can be expected and more continued treatments should be considered exclusively as maintenance therapy. During long-term maintenance therapy, regular intervals should be left without medication to determine the need for continued therapy. However, treatment will not be abruptly discontinued, but the dose will gradually decrease.

Side effects

Like any other medicine, Diazepan Prodes can cause side effects, although not everybody gets them. The most common side effects are fatigue, drowsiness, and muscle weakness. Other effects are less common and include anterograde amnesia (lack of memory), confusion, constipation, depression, diplopia (double vision), difficulty articulating words, headache, hypotension (low blood pressure), incontinence, disorders of libido (sexual appetite), nausea, dry mouth, or secretion of saliva exaggerated, skin rashes, tremor, urinary retention, vertigo and blurred vision; very rarely, abnormal liver blood tests (such as elevation of transaminases and alkaline phosphatase), as well as some cases of jaundice (yellowing of skin and mucous membranes). Paradoxical reactions such as acute arousal, anxiety, sleep disorders, and hallucinations have been observed. If any of these effects occur, treatment should be discontinued. If any of the side effects gets serious, you should immediately tell your doctor or pharmacist.

Pregnancy and lactation

You should consult with your doctor or pharmacist before taking any medicine. If you are pregnant or planning to get pregnant, you should inform your doctor before starting treatment, and he will decide whether or not to take Diazepan Prodes. Diazepan Prodes is eliminated by breast milk and is not recommended for use during lactation; if your doctor thinks you should take it, you should replace breastfeeding.

Special instructions and precautions

Do not take Diazepam Prodes:

-if you are allergic (hypersensitive) to diazepam or any of the other ingredients of Diazepan Prodes;

– if you are dependent on other substances, including alcohol, unless your doctor tells you to;

– if you have closed-angle glaucoma (increased tension in the eye) and have severe chronic hypercapnia (increased carbon dioxide or CO2 in the blood).

Pay special attention with Diazepan Prodes:

  • if you suffer from myasthenia (weakness and fatigue of the muscles), as you may suffer from increased muscle fatigue;
  • if you suffer from moderate respiratory failure, as well as if you suffer from kidney or liver failure. Your doctor should adjust your dose’
  • if you have depression you should note that diazepam only acts on the anxious component, so it is not itself a treatment for depression and may eventually expose some signs of depression.

Diazepam Prodes drug interactions

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. You should not take Diazepan Prodes together with central nervous system medications, such as neuroleptics (medicines used in psychiatry), tranquilizers, antidepressants, hypnotics (sleep facilitators), anticonvulsants (for seizures), analgesics (for pain) and anesthetics, as they increase the sedative action of diazepam.

You should also not take Diazepan Prodes together with cisapride (a medicine used for gastrointestinal disorders) as it causes a transient increase in the sedative effect of diazepam, as well as cimetidine (a medicine for gastric acidity), which increases the risk of somnolence. If you take Diazepan Prodes in conjunction with phenytoin (a medicine for epilepsy), your doctor should monitor your blood levels because they may experience unforeseeable variations causing signs of toxicity or decreased activity or no change.

Overdose

In case of overdose, you may experience drowsiness and sleep, although you may be able to wake up easily. You should notify your doctor immediately or go to the emergency department of the nearest hospital.

If the patient has taken a very high amount of Diazepan Prodes that may lead to coma, lack of reflexes, cardio-respiratory depression, and apnea (a disorder with brief involuntary interruptions of breathing) may occur, requiring appropriate measures (ventilation, cardiovascular support) and also flumazenil, as specific therapy.

Additional information

Diazepan Prodes 10 mg

10, 50, 100

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